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October 1961

New Histopathological and Histochemical Observations Concerning Asteroid Hyalitis

Arch Ophthalmol. 1961;66(4):552-563. doi:10.1001/archopht.1961.00960010554019

Asteroid hyalitis is a condition characterized by the presence of minute solid bodies suspended in a substantially normal vitreous. The opacities, which are stellate, spherical, or discoid, occur in strands or as discrete bodies without orderly arrangement. They may be found throughout the whole vitreous or in any part of it. They appear creamy, flat-white or shiny when viewed with the ophthalmoscope, but sparkle brightly under the more intense illumination of the slit lamp. To various observers, the ophthalmoscopic picture has suggested "stars on a clear night," "the milky way," "an astronomical chart," "snowballs," or "droplets of white paint suspended in water." When the globe is rotated, the bodies move with the vitreous in wave-like undulations; they do not settle to the bottom of the vitreous chamber but return to their original positions after limited excursions. There is no recorded evidence that the presence of these bodies is responsible for