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February 1962

Congenital Cataracts: A Review of 72 Cases Including the Use of Enzymatic Zonulysis in 15 Patients

Author Affiliations

Los Angeles
From the Department of Surgery, Division of Ophthalmology, University of Southern California School of Medicine and the Children's Hospital of Los Angeles.

Arch Ophthalmol. 1962;67(2):143-147. doi:10.1001/archopht.1962.00960020145007

A review of the management of congenital cataracts was spurred by the advent of α-chymotrypsin and a hope that it might offer an improvement over conventional surgical techniques. In my own cases, as well as in those of Cordes1 and Costenbader,2 the results of the earlier methods have left much to be desired.

This paper is based on records of clinic and private patients seen at Los Angeles Children's Hospital since 1946.

The etiology could be ascertained in approximately two-thirds of the cases, but one-third had to be classified as idiopathic (Table 1). The clinic has many darkly pigmented patients, mainly Negro and Mexiican, in whom maternal rubella is not easily diagnosed, therefore in the idiopathic group this diagnosis could have been missed. In addition, familial history of cataracts is often difficult to obtain because of lack of knowledge of any relatives other than the immediate family.


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