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June 1962

Sclerocornea and Associated Congenital Anomalies

Author Affiliations

Howe Laboratory of Ophthalmology, Harvard Medical School, and Massachusetts Eye and Ear Infirmary.

Arch Ophthalmol. 1962;67(6):761-768. doi:10.1001/archopht.1962.00960020761011

Sclerocornea has been described most frequently in conjunction with the entity cornea plana,1-7 but it may also occur as an isolated congenital anomaly.8 The scleralization may affect only a limited area in the peripheral cornea or may involve the entire cornea. In addition to cornea plana, other ocular defects, as well as extraocular anomalies,9 have been noted to accompany sclerocornea.

Seven cases of sclerocornea which we have seen will be described in this paper. These demonstrate different degrees of scleralization and various associated anomalies, some of which have not been previously reported.

Report of Cases 

Case 1.  —A 4-month-old white female was noted to have had cloudy corneas since birth. The infant had been the product of a full-term pregnancy, during which period there had been no maternal illnesses, and the delivery had been uncomplicated. Birth weight was 6 pounds and 7 ounces. The parents, to the

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