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October 1962

Therapy of Lymphosarcoma of the Conjunctiva

Author Affiliations

Edmonton, Alta., Canada
Director, Department of Radiology, University of Alberta Hospital, and Professor of Radiology, University of Alberta.

Arch Ophthalmol. 1962;68(4):498-501. doi:10.1001/archopht.1962.00960030502013

Introduction  Lymphosarcoma of the conjunctiva is a rare disease. Schulz and Heath1 report a series of 1,600 cases of lymphomas of which 14, or 0.9%, involved the conjunctiva. Sugarbaker and Craver2 report on 196 cases of lymphosarcoma confirmed by biopsy. Of these, 1 had secondary involvement of the conjunctiva. Stout3 discusses 218 cases of lymphosarcoma of which none involved the conjunctiva.

Gross Appearance.  —Tumors of the conjunctiva appear as local or diffuse pinkish masses of varying size. Vessels over the surface are prominent. The most important feature of any classification of lymphosarcomas of the conjunctiva is whether the lesion is localized or is part of a generalized disease. One cannot tell from the gross appearance of the conjunctival lesions whether the disease is localized or diffuse. A slightly more extensive classification has been presented by Heath.4

Microscopic.  —The microscopic appearance of lymphosarcoma is quite typical. It