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November 1962

The Use of Liquid Silicone in Retinal Detachment Surgery

Author Affiliations

St. Louis
From the Department of Ophthalmology and the Oscar Johnson Institute, Washington University School of Medicine.

Arch Ophthalmol. 1962;68(5):590-599. doi:10.1001/archopht.1962.00960030594005

Introduction  Silicone rubber has been widely used as implant material in plastic surgery and in retinal detachment procedures.1 Liquid silicone was first injected into the vitreous cavity of rabbits by Stone,2 who reported that silicone fluids of various viscosities were well tolerated and produced "very little change in the rabbit eyes over a period of two years." He went on to predict that it might be possible to find a "viscosity" that would maintain the "clarity" of the vitreous and help in "replacing the retina." Recently, other investigators3-5 have confirmed Stone's observations. However, their animal experiments emphasized the possibilities of complications. Everett4 reported cataract formation following the injection of liquid silicone into the vitreous cavity of rabbits; Galavin5 produced glaucoma by the injection of liquid silicone into the posterior chamber of the rabbit eye.The present study serves a dual purpose: (1) to report further

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