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September 1963

Pilomatrixoma (Benign Calcifying Epithelioma) of the Eyelids and Eyebrow

Author Affiliations

From the Registry of Ophthalmic Pathology, Armed Forces Institute of Pathology, Washington 25, DC.; Assistant Professor of Ophthalmology and Chief, Section of Ophthalmic Pathology, Baylor University College of Medicine (Dr. Boniuk); Chief, Ophthalmic Pathology Branch, and Registrar, Registry of Ophthalmic Pathology, Armed Forces Institute of Pathology (Dr. Zimmerman).

Arch Ophthalmol. 1963;70(3):399-406. doi:10.1001/archopht.1963.00960050401025

Pilomatrixoma is a name that has recently been suggested by Forbis and Helwig5 to replace the terms "calcifying epithelioma" and "benign calcifying epithelioma." Forbis and Helwig believed that the term "pilomatrixoma" conveyed some idea of the generally accepted histogenesis from the hair matrix cells and also avoids the use of the word "epithelioma," which usually indicates a malignant tumor. We agree that this term does have merit and will use it throughout this paper.

This tumor is one that frequently appears to be cystic and is difficult to differentiate clinically from a variety of other cystic lesions3 that may involve the palpebral tissues. There are certain histopathologic features, however, that do enable us to make a definite diagnosis.

A large number of cases have been reported since the original description of the tumor in 1880.11 In 1954 Castigliano and Rominger4 indicated that 243 cases had been

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