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October 1963


Author Affiliations

Ophthalmic Pathology Branch Armed Forces Institute of Pathology Washington 25, DC

Arch Ophthalmol. 1963;70(4):588. doi:10.1001/archopht.1963.00960050590034

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Dr. Verhoeff's letter was referred to Dr. Zimmerman, who offers the following reply.

To the Editor:  —Dr. Verhoeff's comments are, as usual, very pertinent and most welcome. His suggestions that the unusual pigmented lesion described by Dr. Rones and me in the July issue of the Archives of Ophthalmology might have been the result of necrosis of a malignant melanoma and that additional sections might support this thesis cannot be denied. On the other hand, we have seen many examples of severe, even total necrosis in uveal melanomas but never have they resembled the one in question, nor have we previously observed in necrotic melanomas the calcium oxalate and other crystalline deposits which we described and illustrated in our report. About 100 sections were prepared and representative sections were distributed to members of the Ophthalmic Pathology Club at its 1962 meeting. In none of these sections was there found any

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