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January 1964

Behcet's Disease: A Report of 28 Cases

Author Affiliations

Beirut, Lebanon
Department of Ophthalmology, American University Hospital.

Arch Ophthalmol. 1964;71(1):4-14. doi:10.1001/archopht.1964.00970010020003

The earliest description of what today is recognized as Behçet's disease is by Hippocrates in his Third Book of Endemic Diseases.1 Jacobini in 1894 and many others later described the manifestations of this disease, but considered them as complications of certain well-known diseases such as tuberculosis, syphilis, and rheumatism.2 In 1930 Adamentiades presented to the Medical Society of Athens the first recorded case of this condition.3 Whitwell4 described the condition in 1934; he thought it was common but did not know its cause. In 1937, Halusi Behçet5 (pronounced Beh-chet), Professor of Dermatology in Istanbul, drew the various manifestations of this condition together and suggested a new clinical entity, elevating the condition into a syndrome.

Since then numerous reports about this condition have appeared, each usually limited to one or two cases. Sezer6 in 1956 reported 20 cases, and Berlin7 in 1960 reported ten. The

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