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April 1964

The Structure of Retinal Vascular System of the Human Fetus Eye

Author Affiliations

Wills Eye Hospital.

Arch Ophthalmol. 1964;71(4):531-536. doi:10.1001/archopht.1964.00970010547019

Introduction  The architecture and cellular structure of the retinal vessels of the human eye have been described previously.1-5 In the present investigations flat preparations of the eyes of human fetuses and prematurely born infants were made.Development of the retinal vessels in the human fetus eye have been reported by Mann6 and Michaelson.1 Both state that the central retinal artery is recognizable at the 4th month. At this stage a small bulbous swelling appears on the trunk of the hyaloid artery where it passes through the disk. This enlarges and forms small buds which are the beginning of the main branches of the central retinal artery. Other arterial twigs arise from these and ramify in the center of the disk. By the 4th month they have vascularized a small area of the nerve fiber layer around the disk. Then they spread peripherally and at the same time