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June 1964

Choroidal Vascular Patterns in Hypertension

Author Affiliations

Howe Laboratory of Ophthalmology, Harvard University Medical School and Eye Pathology Laboratory, Massachusetts Eye and Ear Infirmary.

Arch Ophthalmol. 1964;71(6):842-850. doi:10.1001/archopht.1964.00970010858014

In a previous paper1 we presented observations on senile vascular patterns of the choroid and their relationship to drusen. The choroidal vessels were prepared in a manner which made possible the simultaneous study, on the flat, of the vessel patterns, of the cells of the vessel wall and of Bruch's membrane.

The present paper will concern the distinctive vascular patterns found in benign and malignant hypertension.

Material for this study was obtained post mortem (131 eyes). The technique of preparation of the choroid has been previously described.1 The stains used for the present study were PAS (periodic acid-Schiff ) with hematoxylin.

The criteria used in designating a case of being one of "benign" or "malignant" hypertension are, somewhat arbitrarily, based on the rate of progression and the severity of the hypertension and renal failure.


1. Age.  —It was previously noted1 that the arterial and arteriolar changes associated

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