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January 1965

Acetazolamide in the Treatment of Postoperative Absent Anterior Chamber

Author Affiliations

San Francisco
From the Department of Ophthalmology, University of California School of Medicine.

Arch Ophthalmol. 1965;73(1):19-24. doi:10.1001/archopht.1965.00970030021006

Most ophthalmic surgeons have encountered the complication of shallow or absent anterior chamber * following cataract extraction. Most often the chamber reforms spontaneously. This tendency toward spontaneous cure makes evaluation of treatment difficult. The complication is of great concern if it persists for more than five days because it is likely to produce peripheral anterior synechias and secondary glaucoma.3,7,13,16, 17,19

Absent chamber following cataract extraction may be present early in the postoperative period or may develop after several days. Early absence usually is due to poor coaptation of the wound edges resulting from faulty suturing, stress on the wound, or interposition of tissue between the margins of the wound. Delayed loss of the anterior chamber has likewise been attributed to a wound leak.7,10,13,18 Other causes have also been postulated, for example, a pupillary block,3,6,24 a choroidal or ciliary body detachment,5,9 a reduction in aqueous formation,15 and