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February 1965


Author Affiliations

Associate Professor, Department of Pathology University of California School of Medicine Los Angeles, Calif 90024

Arch Ophthalmol. 1965;73(2):302. doi:10.1001/archopht.1965.00970030304026

To the Editor:  In the Brief Pathology Case Report, "Leukemic Miliary Nodules in the Retina," by T. Kuwabara and L. Aiello (Arch Ophthal 72:494-497, 1964), it seems to me that the authors do not give an accurate evaluation of the pathologic changes they describe.In a report of eye findings in autopsy cases of patients dying from leukemia, there was ocular involvement in one-half of all cases.1 More than one-fourth of those cases with ocular involvement had leukemic infiltrations of the retina. Observations have since been made on approximately as many more cases and they are in close agreement with those reported.It is the commonly held view that extramedullary leukemic infiltrations in all the various body organs represent foci of proliferation of leukemic cells.2 Such infiltrations ("proliferations") in the retina can not be termed unique, and since such lesions occur in one-fourth of cases with ocular leukemic