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To the Editor:
In spite of the lively discussion in the letter section provoked by Dr. T. E. Acers' article on toxoplasmic retinochoroiditis (Arch Ophthal71:58-62, 1964) a number of pertinent issues have not yet been raised. I find his article extremely interesting, since it focuses on hypersensitivity as the important and frequently overlooked aspect in toxoplasmic retinochoroiditis, and since it indicates that corticoid doses such as given do not apparently impair antitoxoplasmic immunity.Taking a critical view of the procedure employed, we should keep in mind that statistically only a percentage of these patients should have retinochoroiditis due to toxoplasmosis. As there is a certain coincidence of Toxoplasma-test-positivity in the general population, as well as in a patient group, the "normal incidence" must be subtracted from the incidence in a patient group.As focal retinochoroiditis is generally a self-limited lesion there has been historically much erroneous evidence,
Frenkel JK. TOXOPLASMIC RETINOCHOROIDITIS. Arch Ophthalmol. 1965;73(2):304–306. doi:10.1001/archopht.1965.00970030306030
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