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June 1965


Author Affiliations

Department of Ophthalmology University of Nebraska College of Medicine 42nd and Dewey Ave Omaha

Arch Ophthalmol. 1965;73(6):906. doi:10.1001/archopht.1965.00970030908027

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To the Editor:  Dudley and Chick's paper concerning "Corneal Lesions Produced in Rabbits by Extract of Fusarium Moniliforme" (Arch Ophthal 72:346-350 (Sept) 1964) accounts for the clinical differences noted with corneal ulcers of both this species and of Cephalosporium as compared to other fungi. Their explanation that both secrete a proteinase rapidly destructive to corneal collagen correlates well with the relatively rapid destruction that these species cause clinically.Corneas affected with these organisms appear to go down-hill in several days as compared to the slower and more smoldering course of most other fungi. Both of these species of fungi are still listed in many standard pathology texts as saprophytes and not pathogenic to cornea.Time is of the essence with these organisms. Therapeutic results in cases of each have been good if antimycotic therapy is started early.In confused clinical cases laboratory identification is helpful. The usual laboratory method of

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