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September 1965

The Extruded Collagen Suture: Tissue Reaction and Absorption

Author Affiliations

From the Department of Ophthalmology, University of Nebraska College of Medicine.

Arch Ophthalmol. 1965;74(3):371-374. doi:10.1001/archopht.1965.00970040373017

As the search for a more desirable suture material for extraocular muscle surgery continues, various products must be used and evaluated.

Catgut, made of ovine and bovine intestinal submucosa, has the advantage of complete absorption but has the undesirable quality of frequent large and unsightly granuloma formation. Synthetic suture material such as nylon, Supramid, and Mersilene causes little tissue reaction but must be buried and may subsequently erode through the conjunctiva or remain visible through the overlying conjunctiva.1

An extruded collagen suture * has now been made available. This suture, prepared from the deep flexor tendons of cattle, has the advantages of greater uniformity of size, greater purity, and, because it is more homogeneous, should have more dependable rates of absorption. Miller et al2 have reported that the extruded collagen suture is smoother, more pliable, and has greater tensile strength than catgut. They used it successfully in 363 patients