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To the Editor:
In the August 1965 issue of the Archives, Dr. George Howard reviews (the book), Highlights of Ophthalmology 1964. In his statements on αchymotrypsin he editorially states that "the reader will undoubtedly elect not to follow the suggestion of Bedrossian and Weimar that it is unnecessary to irrigate the anterior chamber following its use."Apparently Dr. Howard has ignored the full recommendations based on the laboratory data presented. These recommendations unequivocally stated that no more than 0.2 cc of α-chymotrypsin should be injected to each side. More than this amount is unnecessary. When using these amounts, it is unnecessary and undesirable to add the additional trauma and manipulation of irrigation.Kirsch, in his well documented paper on "Glaucoma Following Cataract Extraction Associated With the Use of Alpha Chymotrypsin" (Arch Ophthal 72:612-620, 1964) injected 2 to 4 cc of enzyme into the posterior chamber. This is five to ten
Bedrossian RH. IRRIGATION AFTER CHYMOTRYPSIN? Arch Ophthalmol. 1965;74(6):882–883. doi:10.1001/archopht.1965.00970040884030
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