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January 1966

Amyloidosis of the Cornea: Report of a Case Without Conjunctival Involvement

Author Affiliations

Washington, DC
From the Registry of Ophthalmic Pathology, Armed Forces Institute of Pathology, Washington, DC 20305.; Work was done during tenure of a Special Fellowship in Ophthalmic Pathology of the National Institute of Neurological Diseases and Blindness, NIH, at the Armed Forces Institute of Pathology (Dr. Stafford). Present address: Department of Ophthalmology, St. Louis University Hospitals, St. Louis, Mo. Ophthalmic Pathology Branch, AFIP (Dr. Fine).

Arch Ophthalmol. 1966;75(1):53-56. doi:10.1001/archopht.1966.00970050055010

The ophthalmic manifestations and a review of the conjunctival and lid lesions on file in the Registry of Ophthalmic Pathology have been presented in the preceding article.1 The purpose of this paper is to present a unique case of amyloid deposition in the corneal epithelium without fibrovascular invasion of the cornea or concurrent amyloid involvement of the surrounding conjunctival tissues. To the best of our knowledge a similar case has not been reported previously.

Report of Case 

Clinical History.  —A white girl was born six weeks prematurely with a birth weight of 3 lb 10 oz (1,645 kg). She was kept in an incubator for four days under an increased tension of atmospheric oxygen. A diagnosis of bilateral retrolental fibroplasia was made at age 3 months, and she became blind in both eyes. Bilateral cataracts and very shallow anterior chambers developed. At about 10½ years of age she began

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