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This volume contains comprehensive reviews of three aspects of multiple sclerosis: epidemiology, clinical studies, and clinical pathology. These reviews are timely and well written. Only the second review on the clinical signs, prognosis, and treatment of multiple sclerosis might interest the practicing ophthalmologist. The eye signs of this disease are covered in detail, and the bibliography appears complete. The prognostic implications of retrobulbar neuritis are covered in detail. The neuro-ophthalmologist will welcome the addition of this book to his reference library.