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March 1966

Band Keratopathy in Gout

Author Affiliations

Gainesville, Fla
From the departments of ophthalmology and pathology, University of Florida College of Medicine, Gainesville.

Arch Ophthalmol. 1966;75(3):367-369. doi:10.1001/archopht.1966.00970050369010

Band keratopathy refers to corneal opacification extending horizontally over the cornea at the level of Bowman's membrane and tending to spare the upper and lower aspects of the cornea. Its clinical appearance has been well described.1 Band keratopathy has long been recognized as a corneal degeneration associated with chronic uveitis and phthisis, but there has been increasing awareness that the hypercalcemia present in a variety of systemic diseases may produce band keratopathy in otherwise normal corneas. On occasion the band keratopathy has improved after treatment of the systemic hypercalcemia.2,3

That the deposits in band keratopathy may actually be calcium has been verified by their histological staining characteristics, as well as by chemical analyses.1 Sisson4 used x-ray spectography to demonstrate large amounts of calcium and phosphorus in corneas with band keratopathy, as well as small quantities of sulfur and silica in advanced cases.

That gout may cause

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