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April 1966

Idiopathic Band Keratopathy

Author Affiliations

From the Max Goldenberg Eye Pathology Laboratory, Michael Reese Hospital and Medical Center, Chicago.

Arch Ophthalmol. 1966;75(4):505-507. doi:10.1001/archopht.1966.00970050507012

The term "band keratopathy" has been ascribed to a clinical and pathological entity most frequently associated with either hypercalcemia1,2,3 (as a manifestation of vitamin D intoxication, parathyroid adenoma, sarcoidosis, uremia, milk alkali syndrome, and immobilization syndrome), or with a local degenerative process (ie iridocyclitis, absolute glaucoma, or phthisis bulbi).

This case report of band keratopathy is presented because of the unusual absence of any associated hypercalcemia or local degenerative process.

Report of Case 

Clinical Summary.  —The patient is a 62-year-old white woman with an eight-year history of open-angle glaucoma which has been medically controlled with topical carbachol and systemic methazolamide (Neptazane). In May, 1963, fine granular deposits were noted paracentrally in the subepithelial layers of the inferior nasal quadrants of both corneas. These lesions slowly progressed in density maintaining a similar configuration and at the time of admission in March 1965, there was noted slight visual impairment of the

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