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September 1966

Localized Aspergilloma of the Eyelid: Treatment With Local Amphotericin B

Author Affiliations

Ann Arbor, Mich
From the departments of ophthalmology, dermatology, and pathology of the University of Michigan Medical Center, Ann Arbor, Mich.

Arch Ophthalmol. 1966;76(3):322-324. doi:10.1001/archopht.1966.03850010324003

Isolated aspergillosis infection of the eyelid in an otherwise healthy young man was successfully treated by injections of amphotericin B directly into the lid granuloma.

Report of a Case  A 27-year-old Negro man first came to the out-patient clinic of the University of Michigan Medical Center on Jan 16, 1963, presenting an ulcerating lesion of the right upper lid (Fig 1), which had been present for about three weeks. He exhibited inactive corneal scars with superficial vascularization in both eyes, which explained his vision of OD: 20/200 and OS: 20/100. These corneal scars were thought to be due to old phlyctenular keratitis. The eyes were otherwise normal. General physical examination of the patient failed to reveal any evidence of other disease. There was no history of any significant previous illness. Results of serologic tests for syphilis were negative and findings of x-ray examination of the chest were normal.A biopsy