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September 1966

Polygeline as a Vitreous Substitute: II. Clinical Results

Author Affiliations

From the Eye Clinic of the University of Amsterdam, Netherlands.

Arch Ophthalmol. 1966;76(3):374-377. doi:10.1001/archopht.1966.03850010376014

In a previous article the experimental replacement of vitreous by polygeline (Haemaccel, Great Britain and Germany) in rabbits was discussed.1 Since the results of these experiments were favorable, the author applied the solution clinically in cases of retinal detachment.

Material and Method  The commercially available 3.5% solution of polygeline was used in 15 patients with retinal detachment. A new sterile bottle was opened for each patient to prevent bacteriological contamination during aspiration which might be disastrous for the eye in view of the fact that polygeline is a good culture medium.Polygeline was used subsequent to scleral diathermy, in most patients combined with scleral resection, according to the method described by Hagedoorn and Velzeboer.2 Injection of the drug was resorted to only when, after removal of subretinal fluid by a sclerochoroidal incision, the ocular tension remained low despite shortening of the eyeball. In our operating room a sterile