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October 1966

Intraocular Pressure and Its Response to Topical Corticosteroids in Diabetes

Author Affiliations

St. Louis
From the Department of Ophthalmology and the Oscar Johnson Institute, Washington University School of Medicine, St. Louis.

Arch Ophthalmol. 1966;76(4):477-483. doi:10.1001/archopht.1966.03850010479003

A high prevalence of elevated intraocular pressures in the diabetic population is less striking in those with proliferative diabetic retinopathy than in those without proliferative changes. In both adult and juvenile groups without proliferative retinopathy, there is a significantly higher prevalence of elevated intraocular pressure after application of topical corticosteroids than in the nondiabetic population. In contrast, the distribution of corticosteroid response in the group of diabetics with proliferative retinopathy resembles more closely that in the nondiabetic volunteer population and differs significantly from that in diabetics without proliferative changes. Speculations concerning the relationship of intraocular pressure and corticosteroid responsiveness to the development of proliferative diabetic retinopathy are presented.

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