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January 1967

Ring-Shaped Limbal Tumor: Secondary to Unrecognized Diffuse Malignant Melanoma of the Uvea

Author Affiliations

Washington, DC
From the Registry of Ophthalmic Pathology, Armed Forces Institute of Pathology, Washington, DC. Drs. Spaulding and Green are Special Fellows in Ophthalmic Pathology, National Institute of Neurological Diseases and Blindness, National Institutes of Health, at the Armed Forces Institute of Pathology, Washington, DC.

Arch Ophthalmol. 1967;77(1):76-80. doi:10.1001/archopht.1967.00980020078016

The most prominent feature of this case was a large, ring-shaped, nonpigmented mass that occupied almost the entire limbus. Neither the clinical nor the gross examination of the enucleated eye, including the use of a dissecting microscope, aided in making the correct diagnosis. Microscopic examination revealed the limbal mass to be an extra-scleral extension of an extremely diffuse malignant melanoma of the uvea.

The unique appearance of this limbal extension from an uncommon form of malignant melanoma prompted this case report.

Report of Case  A 70-year-old man had been seen one year prior to enucleation, with a one-month history of a blind, painful eye. At that time he had refused enucleation. When he returned with the same complaints, the examination revealed a large, elevated, doughnutshaped limbal mass. This lesion had not been noted previously. In addition corneal edema, a heavy aqueous flare, posterior synechiae, a mature cataract, and secondary

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