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The letter from Dr. Sanders was referred to Dr. Liebman who offers the following reply:
To the Editor:
The report of Staple et al (1964) described a 4-month-old patient with cutaneous xanthomas, a retrobulbar mass, and destructive changes in the bony orbit. The pathology of these lesions features lipidized histiocytes in a granulomatous configuration. The original report covered only a two-month follow-up period, and the information which it presented could tentatively place the patient in a category of either juvenile xanthogranuloma or Schüller-Christian syndrome. The valuable long-term follow-up reports appeared in 1965 and 1966 (after our paper had been prepared for publication). This more recent information, indicating that there had been only minor extension of the disease in the subsequent three years, does support Dr. Sanders' original diagnosis of juvenile xanthogranuloma. It should be noted, however, that the xanthomatous lesions of juvenile xanthogranuloma, xanthoma disseminatumm and the Schüller-Christiana
Liebman SD, Crocker AC, Geiser CF. CORNEAL XANTHOMAS-Reply. Arch Ophthalmol. 1967;77(1):145. doi:10.1001/archopht.1967.00980020147031
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