[Skip to Navigation]
February 1967

Endogenous Mycotic Panophthalmitis Caused by Blastomyces dermatitidis: Report of a Case and a Review of the Literature

Author Affiliations

Washington, DC
From the Registry of Ophthalmic Pathology, Armed Forces Institute of Pathology, Washington, DC. Drs. Spaulding and Green were Special Fellows in Ophthalmic Pathology, National Institute of Neurological Diseases and Blindness, National Institutes of Health, at the Armed Forces Institute of Pathology, Washington.

Arch Ophthalmol. 1967;77(2):217-222. doi:10.1001/archopht.1967.00980020219012

NORTH AMERICAN blastomycosis, a chronic fungus disease caused by Blastomyces dermatitidis, may rarely involve the ocular structures either by direct extension from lesions involving the face and eyelids1,2 or by hematogenous dissemination from a primary pulmonary lesion. Churchill and Stober,3 in 1914, reported the first case of "metastatic" or endogenous endophthalmitis, and since then three additional cases with intraocular involvement have been reported (Table).

The purpose of this paper is to report a case of endogenous blastomycotic panophthalmitis, clinically unsuspected, that developed in a patient who presented no evidence of systemic or cutaneous disease when enucleation was performed because of a painful, blind eye.

Report of Case  A 73-year-old white man began to complain of pain in his left eye on Oct 15, 1965. During the following week the eye became increasingly painful and inflamed, and all useful vision was lost. He was started on topical steroids and