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April 1967

Congenital Rubella Cataracts: Surgical Results and Virus Recovery From Intraocular Tissue

Author Affiliations

From the Department of Ophthalmology, Hospital of Pennsylvania, Wistar Institute of Anatomy and Biology, Philadelphia General Hospital, Veterans Administration Hospital and the Children's Hospital of Philadelphia.

Arch Ophthalmol. 1967;77(4):440-444. doi:10.1001/archopht.1967.00980020442005

THIS PAPER presents (1) the results from operating upon 49 eyes with congenital rubella cataracts; (2) the outcome of attempts to recover the rubella virus from intraocular specimens from some of these eyes; and (3), a suggestion that the poor surgical outlook for congenital rubella cataracts may be partially explained by the persistence of the virus within the eye. A total of 19 cultures was taken from 16 different eyes; 17 of which were obtained at the time of surgery, and two immediately following enucleation. The oldest child from whose eyes; 17 of which were obtained at the time of age.

The diagnosis of congenital rubella cataract was made clinically in nine patients (Table 1; patients 1 through 9) who were born prior to the development of techniques for rubella virus isolation. The validity of the diagnosis was determined by the presence of at least two thirds of the classical