A snail-like formation of pigment epithelium with interstitial layers of hyalin-like substance was observed in the subretinal fluid of an eye with long-standing secondary detachment. This spiral formation is thought to be formed by the growth of either free-floating daughter cells of proliferated pigment epithelium or a druse that separated from the disc margin.
Wolter JR. Proliferating Pigment Epithelium: Producing a Simple Organoid Structure in the Subrentinal Space of a Human Eye. Arch Ophthalmol. 1967;77(5):651–654. doi:10.1001/archopht.1967.00980020653016
Coronavirus Resource Center
Customize your JAMA Network experience by selecting one or more topics from the list below.
Create a personal account or sign in to: