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June 1967

Anti-DNA in the Sera of Patients With Uveitis

Author Affiliations

Columbus, Ohio
From the departments of microbiology and ophthalmology, Ohio State University, Columbus.

Arch Ophthalmol. 1967;77(6):777-779. doi:10.1001/archopht.1967.00980020779011

As compared with controls, significant numbers of sera from patients with active presumed histoplasmic chorioretinitis (12/51) and with active presumed toxoplasmic chorioretinitis (6/30) contained antibody to deoxyribonucleic acid as measured by bis-diazotized-benzidine (BDB) indirect hemagglutination. Thus it is suggested that autoimmune mechanisms may contribute to some level in these disorders, and further studies are indicated.