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September 1967

A Current Evaluation of Corneal Prosthetic Devices

Arch Ophthalmol. 1967;78(3):269-271. doi:10.1001/archopht.1967.00980030271001

NEARLY 200 years ago, there appeared a reference to the restoration of corneal transparency by the substitution of treated glass.1 One-hundred years ago2 note was made of the three-year retention of a glass plate in a rabbit's cornea. Several years later implantation of a glass disc in a human patient was recorded.3 Since that time there have appeared numerous articles describing the use of various alloplastic materials in the cornea. The literature has been reviewed by Stone,4 Gyorffy,5 Cardona,6 and Castroviejo.7 Glass, celluloid, and quartz were used until World War II when, with the development of plexiglass for airplane windows, an inert material became available which could be cut and surfaced with relative ease. Military injuries had demonstrated it to be unusually well tolerated by the cornea. Since all ophthalmic surgeons were unhappily aware that many diseased corneas do not react well to