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Since keratoplasty has become a commonplace procedure with relatively standardized techniques, interest has been centering more and more upon the biological aspects of grafting. Dr. Leigh reviews current knowledge in this area and then gives his own experiences concerning techniques, complications, and indications for surgery based on some 600 cases. Such information is most valuable since it is only by the pooled efforts of many surgeons that the technical and physiopathological problem of homografting will be solved.