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October 1967

Experimental Hypotony With Silastic

Author Affiliations

Syracuse, NY
From the Department of Ophthalmology, State University of New York Upstate Medical Center, Syracuse, NY. Dr. Belkowitz is presently at the Henry Ford Hospital, Detroit.

Arch Ophthalmol. 1967;78(4):503-511. doi:10.1001/archopht.1967.00980030505018

Injection of silastic under the anterior uvea in rabbits resulted in a decrease of ocular tension lasting for two to five months when one fourth to one half of the ciliary body was detached. The recovery pattern showed a characteristically gradual, exponential rise of tension. Detachment of an equal amount of anterior choroid resulted in hypotony for one month, with a much steeper recovery curve. The histological findings and recovery course suggest that these implants cause hypotony by their traumatic effects rather than by the detachment space they create. The clinical implications of these results and of several operative complications are discussed.

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