A vitreoretinal traction syndrome at the posterior pole of the fundus occurs as a rare complication of posterior vitreous separation. Residual vitreoretinal adherence at the macula may be diagnosed by slit-lamp microscopy using a fundus contact lens. The symptoms usually disappear after the adherence separates. Permanent cystic degeneration results if the adherence persists. A late wrinkling or contraction of the inner layer of the retina may occur as a sequel to vitreoretinal traction. A characteristic appearance results consisting of wrinkling at the level of the internal limiting membrane, increased tortuosity of the perimacular vessels, and a preretinal membrane. The cause of this late maculopathy remains speculative but probably results from a proliferation of residual vitreous remaining on the retina after posterior vitreous separation. This causes contraction or wrinkling of the inner retinal layers.
Jaffe NS. Macular Retinopathy After Separation of Vitreoretinal Adherence. Arch Ophthalmol. 1967;78(5):585–591. doi:10.1001/archopht.1967.00980030587005
Monkeypox Resource Center
Customize your JAMA Network experience by selecting one or more topics from the list below.