An atypical contact dermatitis to a proparacaine ophthalmic solution provoked drying and fissuring of the fingertips of an ophthalmologist. Patch testing proved the proparacaine to be the cause, and the dermatitis ceased when other anesthetic agents were substituted.
March C, Greenwood MA. Allergic Contact Dermatitis to Proparacaine. Arch Ophthalmol. 1968;79(2):159–160. doi:https://doi.org/10.1001/archopht.1968.03850040161008
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