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February 1968

Anaphylactoid Reaction to Intravenously Administered Fluorescein

Author Affiliations

Washington, DC; Chula Vista, Calif
From Ophthalmology Service, Walter Reed General Hospital, Walter Reed Army Medical Center, Washington, DC.

Arch Ophthalmol. 1968;79(2):161-162. doi:10.1001/archopht.1968.03850040163009

FLUORESCEIN, administered intravenously, has been discussed frequently in the current ophthalmologic literature. However, no mention has been made of serious adverse drug reactions, and for that reason, this case is being reported.1-7

Report of a Case  The patient is a 30-year-old white man, a physician, with a childhood history of hay fever. He has also had allergic reactions in the past that have been manifested by partial respiratory obstruction and pruritus of the middle ear and oropharynx. These occurred after he ate ripe cantaloupe, cucumber, or watermelon. The patient now avoids these foods and has had no allergic reactions since 1962.For one week prior to admission to the hospital, the patient had uniocular metamorphopsia. He was seen at the Walter Reed General Hospital Eye Clinic, and a diagnosis was made of detachment of the posterior vitreous with wrinkling of the internal limiting membrane of the retina of his

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