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April 1968

Amyloid in Corneal Dystrophies: Differentiation of Lattice From Granular and Macular Dystrophies

Author Affiliations

Washington, DC
From the Registry of Ophthalmic Pathology, Armed Forces Institute of Pathology, Washington, DC. Dr. Smith is presently with the Department of Ophthalmology, Washington University School of Medicine, St. Louis.

Arch Ophthalmol. 1968;79(4):407-412. doi:10.1001/archopht.1968.03850040409008

Lattice dystrophy of the cornea can be differentiated histologically from granular and macular dystrophies by the use of those stains that are employed in the histologic detection of amyloid. Only the stromal lesions of lattice dystrophy give consistently positive reactions for amyloid. The histologic, histochemical, and electron microscopic similarities of the lesions of lattice dystrophy and amyloid are striking, and the question is raised as to what, if any, is the relationship between these two entities.