The technique of suprachoroidal space injection was utilized to produce experimental toxoplasmic retinochoroiditic lesions in rabbits. The lesion produced by the injection of the Beverley strain of Toxoplasma gondii closely resembled the naturally occurring disease in man, but it was less exudative and regressed spontaneously after only two to three weeks of activity. This experimental model may prove to be of use in studying pathogenetic mechanisms and therapy in this disease.
Nozik RA, O'Connor GR. Experimental Toxoplasmic Retinochoroiditis. Arch Ophthalmol. 1968;79(4):485–489. doi:10.1001/archopht.1968.03850040487016
Customize your JAMA Network experience by selecting one or more topics from the list below.