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May 1968

Alveolar Rhabdomyosarcoma of Paranasal Sinuses and Orbit

Author Affiliations

New Orleans
From Department of Ophthalmology, Tulane Medical School, New Orleans.

Arch Ophthalmol. 1968;79(5):574-577. doi:10.1001/archopht.1968.03850040576014

Although rhabdomyosarcoma is the third most common tumor found in children, rhabdomyosarcoma of the paranasal sinuses and orbit is an infrequent tumor in adults.1,2 In the case herein reported an alveolar rhabdomyosarcoma which arose from the paranasal sinuses of a 26-year-old white physician illustrated several unusual features. Although the tumor arose in the paranasal sinuses, the presenting symptoms were those of retrobulbar neuritis secondary to sinusitis. Another unusual feature was the observation of a histologic change in the character of the tumor following radiation and chemotherapy.

Report of a Case  A 26-year-old white male physician was first seen by one of us (O.H.D.) because he had observed a sudden decrease of vision in the right eye on awakening that morning. The visual acuity in the right eye was decreased to 20/100. A paracentral scotoma may have been present, but this could not be demonstrated with certainty. (Several weeks later,