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June 1968

A Study of Simulated Vitreous Hemorrhages Using Labeled Blood

Author Affiliations

New York
From the Department of Ophthalmology, College of Physicians and Surgeons, Columbia University, New York.

Arch Ophthalmol. 1968;79(6):755-758. doi:10.1001/archopht.1968.03850040757018

Rabbit eyes were injected with radioactive chromium (51Cr) tagged whole, or lysed blood, or51 Cr in simple solution. Serial radiation counts showed that the rates of removal of these injected materials were significantly different, indicating that particle size is the most important factor in removal of material from the vitreous, and that hemolysis is a rate-determining step in the absorption of vitreous hemorrhages. Ophthalmoscopic studies showed that the vitreous of the eyes injected with lysed blood cleared more rapidly than those injected with whole blood, but residual opacity remained in both.