The effect of oxygen exposure combined with simultaneous administration of chloroquine or phenothiazine has increased greatly the incidence of oxygen-induced retinal detachment. Prolonged treatments resulted in extensive retinal degeneration.
Beehler CC, Roberts W. Experimental Retinal Detachments: Induced by Oxygen and Phenothiazines. Arch Ophthalmol. 1968;79(6):759–762. doi:https://doi.org/10.1001/archopht.1968.03850040761019
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