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August 1968

The Effects of Progestins and Estrogens on

Author Affiliations

From Howe Laboratory of Ophthalmology, Harvard Medical School, Massachusetts Eye and Ear Infirmary, Boston.

Arch Ophthalmol. 1968;80(2):230-234. doi:10.1001/archopht.1968.00980050232017

Progestins and estrogens were found to increase lens permeability to cations in vitro but had no effect on active cation transport. It was dose related and dependent on the duration of exposure. The increase in cation permeability, determined by the rubidium 86 (86Rb) runout method, was accompanied by an increase in lens water, an alteration in cation content, and a loss of lens clarity.

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