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Article
September 1968

MYCOPLASMA IN THE ETIOLOGY OF ANTERIOR AND POSTERIOR UVEITIS: AN EXPERIMENTAL MODEL

Arch Ophthalmol. 1968;80(3):416. doi:10.1001/archopht.1968.00980050418030

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Abstract

To the Editor.  —The genus Mycoplasma has been cited in the literature as a possible etiologic agent of uveitis in man. In these patients, the agent has not, however, been isolated directly from the eye but only from other parts of the body.The present communication reports the first experimental model of Mycoplasma anterior and posterior uveitis. It has been possible not only to isolate the agent directly from the diseased eye, but also to demonstrate a progressive and significant rise in antibody titer to the agent in the serum of the experimental animals.The procedure adopted was as follows. New Zealand rabbits received inoculations of two species of live Mycoplasma, one into the anterior chamber of the right eye and the other into the anterior chamber of the left eye. The species inoculated into the left eye was used as a control since it was found by previous experiments

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