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October 1968

Wilms' Tumor Metastatic to the Orbit

Author Affiliations

New Orleans
From the Department of Pathology, Louisiana State University Medical Center and Charity Hospital, New Orleans.

Arch Ophthalmol. 1968;80(4):480-483. doi:10.1001/archopht.1968.00980050482013

A wilms' tumor (nephroblastoma) metastatic to both orbits is presented. Reports of orbital metastases from this tumor are rare and this is the first histopathologic study presented in the ophthalmic literature.

Report of a Case  A 2-year-old Negro boy was admitted to Charity Hospital of New Orleans on Aug 8, 1966, with a history of hematuria and an abdominal mass of the left side. A histological diagnosis of Wilms' tumor was made following surgical exploration and nephrectomy. Bilateral involvement of the orbits and eyelids was noted soon after the original admission. In spite of several courses of chemotherapy and irradiation, the child died one year later.At autopsy, the patient was found to be extremely cachectic and disfigured due to extensive tumor metastasis. A large prominent bulging mass was present over the frontal area and left orbit (Fig 1). The left orbit was filled with tumor, leaving almost no recognizable

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