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November 1968

Changes in Kayser-Fleischer Ring During Treatment of Hepatolenticular Degeneration

Author Affiliations

From the Division of Ophthalmology, Department of Surgery (Dr. Mitchell) and the Division of Neurology, Department of Medicine (Dr. Heller), Case Western Reserve University School of Medicine, Cleveland.

Arch Ophthalmol. 1968;80(5):622-625. doi:10.1001/archopht.1968.00980050624008

Kayser-Fleischer rings were observed in two patients over a three-year period during treatment of hepatolenticular degeneration (Wilson's disease). The clinical improvement of these patients did not correlate with changes in the corneal deposits. The neuropathologic implications of these observations are discussed.

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