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November 1968

Modification of Latent Nystagmus: Part I

Author Affiliations

St. Louis; Iowa City
From the Department of Ophthalmology, Washington University, St. Louis (Dr. Windsor) and the Department of Ophthalmology, University of Iowa, Iowa City.

Arch Ophthalmol. 1968;80(5):657-663. doi:10.1001/archopht.1968.00980050659014

A study of the effect of cycloplegia-mydriasis on the parameters of latent ocular nystagmus is reported. Cyclopentolate 1% (Cyclogyl) appears to decrease the amplitude, velocity, and, to a lesser extent, frequency of latent ocular nystagmus in a majority of the cases studied. This was associated with improvement in the monocularly recorded visual acuity. The interaction of latent nystagmus with manifest nystagmus, gaze nystagmus, and opticokinetic nystagmus, and their modification by cycloplegia indicated that separate neurologic centers are operative, and one may dominate another under different conditions. Possible explanations of the effect of the drug on nystagmus are discussed in relation to current theories of the etiology of latent nystagmus.