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February 1969

Effects of Cryopexy Upon the Retinal Vasculature

Author Affiliations

Iowa City
From the Department of Ophthalmology, College of Medicine, University of Iowa, Iowa City.

Arch Ophthalmol. 1969;81(2):254-258. doi:10.1001/archopht.1969.00990010256019

The histopathologic effects of cryopexy on the retinal vasculature of the dog were studied. Ranges of cryopexy considered therapeutic were used, and the vessels were examined in retinal whole mounts prepared by trypsin digestion. Cryosurgical applications of -30 C to -40 C for one to three seconds produced necrosis of retinal capillaries, first apparent three days following treatment. Pigment deposition and hypercellularity were noted in the venules, while the arterioles remained relatively unaffected.