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February 1969

Hereditary Hemorrhagic Telangiectasis (Rendu-Osler-Weber Disease) With Filamentary Keratitis

Author Affiliations

From the Cornea Service, Wills Eye Hospital and Research Institute, Philadelphia. Dr. Wolper is a fellow of the Heed Ophthalmic Foundation.

Arch Ophthalmol. 1969;81(2):272-277. doi:10.1001/archopht.1969.00990010274022

A case of Rendu-Osler-Weber disease in which filamentary keratitis intermittently occurred is presented. Ocular symptomatology and findings are described including foreign-body sensation and intermittently sanguinous tears. Biopsy of a conjunctival vascular lesion from the right lower lid revealed tortuous abnormally dilated vascular channels within the epithelium. Differential diagnosis of conjunctival telangiectases and bleeding from the conjunctiva is discussed with speculation into a possible relationship between the vascular anomalies in the conjunctiva and the filamentary keratitis.

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