Toxoplasmic retinochoroiditis in 63 referred patients first occurred between ages 7 and 57 with a mean age of 25 years. Each patient had an average of 2.7 episodes, with a range of 1 to 13. The episodes averaged 4.2 months, ranging from one week to two years. Three morphologic variations were seen: large destructive, punctate inner retinal, and punctate deep with subretinal fluid at the macula. These types had different prognoses for vision, episode duration, and complications. Recognition of variations is essential for design of therapeutic trials.
Friedmann CT, Knox DL. Variations in Recurrent Active Toxoplasmic Retinochoroiditis. Arch Ophthalmol. 1969;81(4):481–493. doi:10.1001/archopht.1969.00990010483005
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