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June 1969

Proteins in Human Tears: I. Immunoelectrophoretic Patterns

Author Affiliations

Los Angeles
From the Laboratory of Ophthalmic Immunology, Cedars-Sinai Medical Research Institute, Cedars-Sinai Medical Center (Drs. Sapse and Bonavida), and the Department of Bacteriology, University of California (Drs. Bonavida and Sercarz), Los Angeles. Dr. Stone is presently at the National Institute for Scientific Research, Los Angeles.

Arch Ophthalmol. 1969;81(6):815-819. doi:10.1001/archopht.1969.00990010817012

Immunoelectrophoresis of tears yielded seven visible components. These were identified with specific antisera as specific tear prealbumin, serum albumin, ceruloplasmin, transferrin, IgA, IgG, and lysozyme. Specific tear prealbumin is a unique tear component. Tear IgA has a specific antigenic moiety not present in serum IgA. The importance of these seven proteins is discussed.

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