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June 1969

Prophylaxis of Herpetic Keratoconjunctivitis With Interferon InducersPreliminary Observations

Arch Ophthalmol. 1969;81(6):840-842. doi:10.1001/archopht.1969.00990010842016

Topical or systemic administration of synthetic double-stranded polyinosinic acid:cytidilic acid RNA prevented the establishment of herpetic keratoconjunctivitis in rabbits. The degree of systemic protection was directly related to the serum level of interferon induced.