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June 1969

Prophylaxis of Herpetic Keratoconjunctivitis With Interferon Inducers: Preliminary Observations

Author Affiliations

New York; Bethesda, Md
From the Department of Ophthalmology of the New York Medical College (Drs. Park and Galin) and the Laboratory of Viral Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, and Public Health Service, Bethesda, Md. Dr. Billau is a Guest Scientist at the National Institutes of Health, and an "Aspirant" of the Belgian N.F.W.O.

Arch Ophthalmol. 1969;81(6):840-842. doi:10.1001/archopht.1969.00990010842016

Topical or systemic administration of synthetic double-stranded polyinosinic acid:cytidilic acid RNA prevented the establishment of herpetic keratoconjunctivitis in rabbits. The degree of systemic protection was directly related to the serum level of interferon induced.

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